Trimethoprim-sulfamethoxazole in murine toxoplasmosis.
نویسنده
چکیده
The combination trimethoprim-sulfamethoxazole had no greater activity in a murine model of toxoplasmosis than did sulfamethoxazole alone.
منابع مشابه
Unusual presentation of primary toxoplasmosis infection in a kidney-transplant patient complicated by an acute left-ventricular failure
Although primary toxoplasmosis is a rare event following kidney transplantation, it can be life threatening. This report describes this complication. The patient presented with high-grade fever, haemolytic anaemia and haemophagocytic-syndrome-related pancytopaenia. Toxoplasma gondii diagnosis was ascertained by blood and bone-marrow PCR assays. After 6 weeks with Clindamycin plus pyrimethamine ...
متن کاملSulfadiazine-induced crystalluria and renal failure in a patient with AIDS.
Cerebral toxoplasmosis is one of the most treatable opportunistic infections of the central nervous system in patients with the acquired immunodeficiency syndrome (AIDS).l,2 A combination of sulfadiazine and pyrimethamine is the therapy of choice, producing a favorable clinical response in 68 to 95 percent of patients receiving this regimen.3,4 Reports of sulfadiazine-induced crystalluria and r...
متن کاملA prospective randomized trial of azithromycin versus trimethoprim/sulfamethoxazole in treatment of toxoplasmic retinochoroiditis
PURPOSE To assess the efficacy of oral azithromycin in the treatment of toxoplasmic retinochoroiditis. METHODS A randomized interventional comparative study was conducted on 14 patients with ocular toxoplasmosis who were treated with oral azithromycin and 13 patients who were treated with oral trimethoprim/sulfamethoxazole for 6-12 weeks. The achievement of treatment criteria in the two group...
متن کاملShort-term Results of Two Treatment Regimens in Ocular Toxoplasmosis: Trimethoprim/Sulfamethoxazole versus Pyrimethamine and Sulfadiazine
Purpose: To compare the efficacy of classic treatment for ocular toxoplasmosis (pyrimethamine, sulfadiazine and predinsolone) with a regimen consisting of trimethoprim/sulfamethoxazole (TMP/SMX) [co-trimoxazole] plus predinsolone. Methods: In a prospective randomized single-blind clinical trial, 59 patients with active ocular toxoplasmosis were randomly assigned to two treatment groups: 29 were...
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2. Wreghitt T, Gray J, Pavel P, et al. Efficacy of pyrimethamine for the prevention of donoracquired Toxoplasma gondii infection in heart and heart-lung transplant patients. Transplant Int 1992; 5:197–200. 3. Orr K, Gould F, Short G, et al. Outcome of Toxoplasma gondii mismatches in heart transplant recipients over a period of 8 years. J Infect 1994; 29:249–53. 4. Holliman RE, Johnson JD, Adams...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 9 2 شماره
صفحات -
تاریخ انتشار 1976